王洁

发布者:JDB游戏官方网站313发布时间:2024-11-04浏览次数:3528

姓名

王洁

性别

籍贯

政治面貌

中共党员

毕业院校

浙江大学

专业

微生物学

学历

博士研究生

学位

博士研究生

邮箱地址

jiewang@scau.edu.cn

通讯地址

广州天河五山路483号JDB游戏官方网站415

联系电话

13423618571

所在院系

JDB游戏官方网站生工系

职称

副研究员

担任职务

个人简介

王洁,女,19878月出生,中共党员,主要从事功能微生物(益生菌)生理与代谢研究,包括:1)功能微生物(益生菌)及其功能基因资源开发与利用;2)益生菌及其功能性食品的健康功效及其作用机制;3)食品功能成分生物转化及有害成分(如真菌毒素)生物降解;已在Food &FunctionLWTCritical Reviews in Food Science and NutritionFood Science and Human WellnessInternational Reviews of ImmunologyToxinsFrontiers in MicrobiologyEnvironmental MicrobiologyApplied Microbiology and BiotechnologyFungal Genetics and BiologyFungal Biology、中国生物工程杂志、食品科学、现代食品科技等国内外期刊上以第一或通讯作者、共同第一或通讯作者发表SCI论文30余篇,中文核心论文4篇;以第一发明人申请国家发明专利11项,授权国家发明专利9项,转让发明专利1项。

研究方向

1、功能微生物及其基因功能分析

2、益生菌及其功能性食品的健康功效

3、食品功能成分生物转化及有害成分(如真菌毒素)生物降解

承担教学

《食品微生物学》、《食品微生物学实验技术》、《微生物制剂》、《微生物学》、《饮食、菌群与健康》

科研项目


  1. 广东省自然科学基金-青年提升项目,SUMO化修饰调控黑曲霉α-淀粉酶产量的作用机制,2023.012025.12,主持

  2. 广东省重点领域研发计划项目-子课题茶多酚加工关键技术研发与产品开发2021.122024.11主持

  3. 广东省重点领域研发计划项目-子课题,发酵食品精准制造关键技术及产业化示范,2020.012024.12主持

  4. 广东省科技专项资金项目,新型浓香型花生油安全生产工艺集成研究,2020.01-2021.12,主持

  5. 华南应用微生物国家重点实验室开放课题,抗铜绿假单胞菌抗菌肽的结构鉴定及抑菌机理,2019.09-2021.08主持

  6. 广州市科技计划项目,抗MRSA抗菌肽的结构鉴定、抑菌机理及其在肉制品保藏中的应用潜能评估2019.042022.03,主持

  7. 国家自然科学青年基金,聚酮合酶pks7pks11对海洋草酸青霉合成Oxalicumone A及其环境适应性的调控机制研究2017.01-2019.12,主持

  8. 广东省重点领域研发计划项目-子课题,特色微生物航天育种技术创新与菌种创制,2019.012021.12主持


学术论文

2020年以来发表的SCI论文:

  1. Yang X, Chen J, Liao Z, Xia Z, Huang H, Huang J, Chen L, Fang X, Gao C, Wang J*. Lactobacillus fermentum WC2020 increased the longevity of Caenorhabditis elegans via JNK-mediated antioxidant pathway. Journal of Food Science 2024, 89: 3713-3728.

  2. Ouyang W, Liao Z, Yang X, Zhang X, Zhu X, Zhong Q, Wang L, Fang X, Wang J*. Microbial composition of water kefir grains and their application for the detoxification of aflatoxin B1. Toxins 2024, 16: 107.

  3. Zhu X, Wang Y, Li S, Peng R, Wen X, Peng H, Shi Q, Zhou G*, Xie X*, Wang J*. Rapid detection of mexX in Pseudomonas aeruginosa based on CRISPR-Cas13a coupled with recombinase polymerase amplification. Frontiers in Microbiology 2024, 15: 1341179.

  4. Chen W#, Wang J#, Du L#, Chen J, Zheng Q, Li P, Du B, Fang X, Liao Z. Kefir microbiota and metabolites stimulate intestinal mucosal immunity and its early development. Critical Reviews in Food Science and Nutrition 2024, 64: 1371-1384.

  5. Zhu Y#, Liu T#, Wang Y, Chen G, Fang X, Zhou G*, Wang J*. ChsA, a Class II Chitin Synthase, Contributes to Asexual Conidiation, Mycelial Morphology, Cell Wall Integrity, and the Production of Enzymes and Organic Acids in Aspergillus niger. Journal of Fungi 2023, 9, 801.

  6. Ye Z#, Yang X#, Deng B, Liao Z, Fang X, Wang J*. Prevention of DSS-induced colitis in mice with water kefir microbiota via anti-inflammatory and microbiota-balancing activity. Food & Function 2023, 14, 6813-6827.

  7. Liu T#, Zhou G#, Du M#, Zhang X, Zhou S, Chen G, Liao Z, Zhong Q, Wang L, Xu X*, Fang X*, Wang J*. 2023. The interplay between (-)-epigallocatechin-3-gallate (EGCG) and Aspergillus niger RAF106, an EGCG-biotransforming fungus derived from Pu-erh tea. LWT-Food Science and Technology 180: 114678.

  8. Du L#, Wang J#, Chen W, Chen J, Zheng Q, Fang X, Liao Z. 2023. Isolation and purification of Bacillus amyloliquefaciens D1 protease and its application in the fermentation of soybean milk to produce large amounts of free amino acids. Applied Biochemistry and Biotechnology. Applied Biochemistry and Biotechnology 195: 451-466.

  9. Peng H, Zhou G, Yang X, Chen G, Chen H, Liao Z, Zhong Q, Wang L, Fang X, Wang J*. 2022. Transcriptomic analysis revealed antimicrobial mechanisms of Lactobacillus rhamnosus SCB0119 against Escherichia coli and Staphylococcus aureus. International Journal of Molecular Sciences 23: 15159.

  10. Zhou G, Ying S, Feng M, Wang J*. 2022. Differential roles of three α-crystallin domain-containing sHsps of Beauveria bassiana in asexual development, multiple stress tolerance and virulence. International Journal of Molecular Sciences 23: 6717.

  11. Chen G, Fang Q, Liao Z, Xu C, Liang Z, Liu T, Zhong Q, Wang L, Fang X, Wang J*. 2022. Detoxification of aflatoxin B1 by a potential probiotic Bacillus amyloliquefaciens WF2020. Frontiers in Microbiology 13: 891091.

  12. Liu T#, Wang J#, Du M, Wang Y, Fang X, Peng H, Shi Q, Xie X, Zhou G. 2022. The interplay between (-)-epigallocatechin-3-gallate (EGCG) and Aspergillus niger RAF106 based on metabolism. Fungal Biology 126: 727-737.

  13. Wang L#, Wang J#, Du L#, Fang X, Liao Z. Application of Weizmannia coagulans in the medical and livestock industry. Annals of Microbiology 72:30

  14. Chen J#, Li Q#, Wang J#, Chen W, Zheng Q, Zhong Q, Fang X, Liao Z. 2022. Comparative analysis of aroma components and quality of Geotrichum candidum after space mutation breeding. Frontiers in Microbiology 13: 908329.

  15. Kashif H#,Yang Y#, Wang J#, Bian H, Lei X, Chen J, Li Q, Wang L, Zhong Q, Fang X, Wang Y, Wei H, Tong Y, Liao Z*. 2022. Comparative study on the weight loss and lipid metabolism by tea polyphenols in diet. Food Science and Human Wellness 11: 697-710

  16. Du L#, Lei X#, Wang J#, Wang L, Zhong Q, Fang X, Li P, Du B, Wang Y, Liao Z*. 2022. Lipopolysaccharides derived from gram-negative bacterial pool of human gut microbiota promote inflammation and obesity development induced obese C57BL/6J pseudo germ free and conventionalized mice. International Reviews of Immunology 41: 45-56

  17. Meng X, Liao Z, Liu T, Hussain K, Chen J, Fang Q, Wang J*. 2021. Vital roles of Pks11, a highly reducing polyketide synthase, in fungal conidiation, antioxidant activity, conidial cell wall integrity, and UV tolerance of Beauveria bassiana. Journal of Invertebrate Pathology 181: 107588

  18. Peng H#, Wang Y#, Wang J#, Li S, Sun T, Liu T, Shi Q, Zhou G, Xie X. 2021.Chemical components of aqueous extracts of Melia azedarachfruitsand their Effects on The Transcriptome of Staphylococcus aureus. Polish Journal of Microbiology 70: 447-459.

  19. Fang Q, Du M, Chen J, Liu T, Zheng Y, Liao Z, Zhong Q, Wang L, Fang X*, Wang J*. 2020. Degradation and detoxification of aflatoxin B1 by tea-derived Aspergillus niger RAF106. Toxins 12: 777.

  20. Liu T, Meng X, Chen J, Fang Q, Wang J*. 2020. Smt3, a homologue of yeast SUMO, contributes to asexual development, environmental adaptation, and host infection of a filamentous entomopathogen. Fungal Biology 124: 924-931.

  21. Wang J, Chen J, Hu Y, Ying SH, Feng MG*. 2020. Roles of six Hsp70 genes in virulence, cell wall integrity, antioxidant activity and multiple stress tolerance of Beauveria bassiana. Fungal Genetics and Biology 144: 103437.


获奖情况

专利

授权专利:

  1. 一株巴氏醋杆菌在抗氧化、减脂和抗衰老中的应用. 王洁, 杨翕淼,. 专利号:ZL202211676676.3

  2. 哈尔滨乳杆菌在抗氧化、抗衰老和减脂中的应用. 王洁, 杨翕淼,. 专利号:ZL202211460858.7

  3. 一株粗糙脉孢菌WC2022菌株及其应用. 王洁,朱晓璇,陈国浚,林蕾,方祥,廖振林,钟青萍,王丽. 专利号:ZL202210676359.5

  4. 一种全细胞转化生产大豆异黄酮苷元的方法. 王洁, 张晓,林蕾,方祥,廖振林,钟青萍,王丽.专利号:ZL202210690071.3

  5. 一株发酵乳杆菌WC2020及其应用. 王洁,杨翕淼,陈健文,房倩安,方祥,廖振林,钟青萍,王丽. 专利号:ZL202210283365.4.

  6. 解淀粉芽孢杆菌WF2020菌株产品及其应用. 王洁,杨翕淼,陈健文,房倩安,方祥,廖振林,钟青萍,王丽,徐纯伟,梁智博. 专利号:ZL202210190719.0.

  7. 一株用于防控黄曲霉毒素B1污染的解淀粉芽孢杆菌及其应用. 王洁,陈国浚,房倩安,方祥,廖振林,钟青萍,王丽,徐纯伟,梁智博. 专利号:ZL202210148253.8.

  8. 一株用于降解黄曲霉毒素B1的暹罗芽孢杆菌WF2019菌株及其应用. 王洁,房倩安,方祥,廖振林,钟青萍. 专利号:ZL201910808563.6

  9. 一种复合生物保鲜剂及其应用. 王洁,刘付茵,钟雪韵,周楚婷,房倩安,方祥. 专利号:ZL201911222220.8. 该专利已转让.