姓名 | 王涓 | 性别 | 女 |
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邮箱地址 | wangjuan@scau.edu.cn; wangjuanjanice@163.com | 通讯地址 | 广州市天河区JDB游戏官方网站 | |
职称 | 研究员 | 所在院系 | JDB游戏官方网站生物工程系 | |
个人简介 | 王涓,研究员,博士生导师。国家重点研发计划课题负责人,“广东特支计划”科技创新青年拔尖人才,中国研究型医院学会细胞外囊泡研究与应用专业委员会委员,广东省食用菌行业协会第四届专家委员会委员。致力于食源性致病菌的危害形成机制、高通量快速检测及防控技术研究。获广东省科技进步奖特等奖(2021)、中国食品科学技术学会技术进步一等奖(2022、2020)、中国轻工业联合会科学技术进步奖一等奖(2022)、安徽省科学技术奖二等奖(2021)等。主持国家重点研发计划课题(2项)、广东省基础与应用基础研究重大项目课题等国家及省部级重大重点项目及课题。近5年以第一作者/通讯作者(含共同)在Chemical Engineering Journal,Biotechnology Advances,Critical Reviews in Food Science and Nutrition 等期刊发表SCI论文22篇(一区Top文章12篇,IF>10论文4篇,IF>5论文18篇);申请PCT专利14件,授权国家发明专利66件;取得软件著作权 1 件;制定行业标准1项。 | |||
研究方向 | 食品微生物安全与健康,食源性致病菌的风险识别、危害形成机制、高通量快速检测及防控技术研究 | |||
承担教学 | 本科生课程: 《食品微生物学(全英)》 《生物工程下游技术(双语)》 《分子生物学》 研究生课程: 《生物工程研究进展》 | |||
科研项目 | 1、畜禽重要食源性病原传播动力学研究及病原和组学数据库构建,国家重点研发计划课题, 2023-2027,390万元,课题负责人 2、食源性致病菌快速高通量检测技术与装备研发,国家重点研发计划课题, 2018-2021,301万元,课题负责人 3、周质蛋白操纵子调控食源性空肠弯曲菌生物膜形成的机制研究,国家自然科学基金青年项目,30万,2019-2021,项目主持人 4、食用微生物科学大数据库构建及资源勘探,国家重点研发计划课题, 2023-2027,90万元,子课题负责人 5、大宗食品中高污染致病性蜡样芽孢杆菌危害形成与防控分子机制,广东省基础与应用基础研究重大项目, 570万,2020-2025,课题4负责人 6、水产品中不携带溶血基因(tdh/trh) 副溶血性弧菌的危害形成机制,国家自然科学基金重点项目,296万元,2018-2021,主要参加 7、岭南特色微生物种质库构建及野生食用菌选育,广东省重点领域研发计划,,2019-2021,1500万元,子课题负责人 8、华南特色功能食品及饲用微生物组学研究与应用,广东省重点领域研发计划,2019-2021,700万元,子课题负责人 | |||
学术论文 | (1) Liu M#, Ding Y#, Ye Q, Wu S, Gu Q, Chen L, Zhang Y, Wei X, Deng M, Zhang J, Wu Q*, Wang J*. Cold-tolerance mechanisms in foodborne pathogens: Escherichia coli and Listeria monocytogenes as examples, Critical Reviews in Food Science and Nutrition, 2024, DOI: 10.1080/10408398.2024.2322141 (2) Shao Y, Xu W, Zheng Y, Zhu Z, Xie J, Wei X, Zhang Y, Zhang J, Wu Q, Wang J*, Ding Y*. Interface coordination achieving excellent optical properties of three-dimensional dendritic gold nanoparticles for immunochromatographic performance, Chemical Engineering Journal, 2023, 455, 140586. (3) Yuan X, Huang Z, Zhu Z, Zhang J, Wu Q, Xue L, Wang J*, Ding Y*. Recent advances in phage defense systems and potential overcoming strategies, Biotechnology Advances, 2023, 65, 108152. (4) Chen M, Wu Q, Zhu Z, Huang A, Zhang J, Bekhit AEA*, Wang J*, Ding Y*. Selenium-enriched foods and their ingredients: As intervention for the vicious cycle between autophagy and overloaded stress responses in Alzheimer’s disease, Critical Reviews in Food Science and Nutrition, 2023, 2, 1-14. (5) Zhong Y#, Liu M#, Ding Y, Wu Q, Zhang J, Ma G, Xu T, Wang Z, Chen M, Xue L, Ye Q, Wang J*, Rapid fluorescence visualization of Yersinia enterocolitica by CRISPR/Cas12a using novel specific target obtained by pan-genome analysis, LWT, 2023, 175, 114500. (6) Tang S#, Yang R#, Wu Q*, Ding Y, Wang Z, Zhang J, Lei T, Wu S, Zhang F, Zhang W, Xue L, Zhang Y, Wei X, Pang R, Wang J*. First report of the optrA-carrying multidrug resistance genomic island in Campylobacter jejuni isolated from pigeon meat. International Journal of Food Microbiology, 2021, 354, 109320. (7) Wang J#, Liu M#, Wang H#, Wu Q*, Ding Y, Xu T, Ma G, Zhong Y, Zhang J, Chen M, Xue L, Ye Q, Zeng H, Yang X, Yang R. Occurrence, molecular characterization, and antimicrobial susceptibility of Yersinia enterocolitica isolated from retail food samples in China. LWT, 2021, 150, 111876. (8) Wang J#, Wang Z#, Zhang J, Ding Y, Ma Z, Jiang F, Nie X, Tang S, Chen M, Wu S, Zeng H, Lei T, Yang X, Zhang S, Wu Q*. Prevalence, antibiotic susceptibility and genetic diversity of Campylobacter jejuni isolated from retail food in China. LWT, 2021, 150, 111098. (9) Zheng Y#, Xu W#, Guo H, Yu S, Xue L, Chen M, Zhang J, Xu Z, Wu Q, Wang J*, Ding Y*. The potential of lactose to inhibit cereulide biosynthesis of emetic Bacillus cereus in milk. International Journal of Food Microbiology, 2024, 411, 110517. (10) Li Y#, Yang X#, Zhang J, Yang S, Zhang S, Chen M, Xue L, Ding Y, Zeng H, Gu Q, Zhang Y, Wei X, Wang J*, Qingping Wu*. Molecular characterisation of antimicrobial resistance determinants and class 1 integrons of Salmonella enterica subsp. enterica serotype Enteritidis strains from retail food in China. Food Control, 2021, 128, 108191. (11) Zhang Y, Wu Q, Forsythe S, Liu C, Chen N, Li Y, Zhang J, Wang J*, Ding Y*.The cascade regulation of small RNA and quorum sensing system: Focusing on biofilm formation of foodborne pathogens in food industry, Food Bioscience, 2023, 52, 102472. (12) Wu S, Zhu Z, Chen M, Huang A, Xie Y, Hu H, Zhang J, Wu Q, Wang J*, Ding Y*. Comparison of Neuroprotection and Regulating Properties on Gut Microbiota between Selenopeptide Val-Pro-Arg-Lys-Leu-SeMet and Its Native Peptide Val-Pro-Arg-Lys-Leu-Met In Vitro and In Vivo. Journal of Agricultural and Food Chemistry, 2023, 71, 32, 12203-12215 (13) Yang L#, Xie X#, Li Y#, Wu L, Fan C, Liang T, Xi Y, Yang S, Li H, Zhang J, Ding Y, Xue L, Chen M, Wang J*, Wu Q*. Evaluation of the Cholesterol-Lowering Mechanism of Enterococcus faecium Strain 132 and Lactobacillus paracasei Strain 201 in Hypercholesterolemia Rats. Nutrients, 2021,13, 1982. (14) Jiang T#, Li Y#, Li L, Liang T, Du M, Yang L, Yang J, Yang R, Zhao H, Chen M, Ding Y, Zhang J, Wang J*, Xie X*, Wu Q*. Bifidobacterium longum 070103 Fermented Milk Improve Glucose and Lipid Metabolism Disorders by Regulating Gut Microbiota in Mice, Nutrients. 2022, 14, 4050. (15) Wang C#, Ye Q#, Jiang A, Zhang J, Shang Y, Li F, Zhou B, Xiang X, Gu Q, Pang R, Ding Y, Wu S, Chen M, Wu Q*, Wang J*. Pseudomonas aeruginosa Detection Using Conventional PCR and Quantitative Real-Time PCR Based on Species-Specific Novel Gene Targets Identified by Pangenome Analysis. Frontiers in Microbiology, 2022, 13, 820431. (16) Li Y#, Chen N#, Wu Q, Liang X, Yuan X, Zhu Z, Zheng Y, Yu S, Chen M, Zhang J, Wang J*, Ding Y*. A Flagella Hook Coding Gene flgE Positively Affects Biofilm Formation and Cereulide Production in Emetic Bacillus cereus. Frontiers in Microbiology, 2022, 13, 897836. (17) Wang C#, Ye Q#, Ding Y, Zhang J, Gu Q, Pang R, Zhao H, Wang J*, Wu Q*. Detection of Pseudomonas aeruginosa Serogroup G Using Real-Time PCR for Novel Target Genes Identified Through Comparative Genomics. Frontiers in Microbiology, 2022, 13, 928154. (18) Wu S, Liao X, Zhu Z, Huang R, Chen M, Huang A, Zhang J, Wu Q, Wang J*, Ding Y*. Antioxidant and anti-inflammation effects of dietary phytochemicals: The Nrf2/NF-κB signalling pathway and upstream factors of Nrf2, Phytochemistry, 2022, 204, 113429. (19) Yang M#, Chen H#, Huang Q, Xie Z, Liu Z, Zhang J, Ding Y, Chen M, Xue L, Wu Q*, Wang J*. Characterization of the Novel Phage vB_VpaP_FE11 and Its Potential Role in Controlling Vibrio parahaemolyticus Biofilms. Viruses, 2022, 14, 264. (20) Zeng Y#, Li Y#, Wu Q*, Zhang J, Xie X, Ding Y, Cai S, Ye Q, Chen M, Xue L, Wu S, Zeng H, Yang X, Wang J*. Evaluation of the Antibacterial Activity and Probiotic Potential of Lactobacillus plantarum Isolated from Chinese Homemade Pickles, Canadian Journal of Infectious Diseases and Medical Microbiology, 2020, 8818989. | |||
获奖情况 | 1、广东省科技进步奖特等奖( 2021年;排名第8/30) 2、中国轻工业联合会科学技术进步奖一等奖(2022年;排名第6/10 ) 3、中国食品科学技术学会-技术进步一等奖(2022年;排名第6/10 ) 4、安徽省科学技术进步奖二等奖(2021年;排名第4/8 ) 5、中国食品科学技术学会-技术进步一等奖(2020年;排名第9/10 ) | |||
专利 | 1、王涓,聂翔,吴清平,等. 空肠弯曲杆菌种特异性分子靶标及其快速检测方法,国家发明专利,ZL201911393433.7 2、王涓,吴清平,丁郁,等. 含有特异性分子靶标的空肠弯曲菌标准菌株及其检测和应用,国家发明专利,ZL202011611248.3 3、王涓,吴清平,丁郁,等. 含有特异性分子靶标的小肠结肠炎耶尔森氏菌标准菌株及其检测和应用,国家发明专利,ZL202011615514.X 4、王涓,肖铠姗,潘琪琪,等. 一株空肠弯曲菌噬菌体 vB_CjeM_WX1 及其应用,国家发明专利,CN202410093503.1 5、王涓,王梓萌,徐天翔,等. 三株具有特异性分子靶标的烈性小肠结肠炎耶尔森氏菌噬菌体及其应用,国家发明专利,CN202410093492.7 6、王涓,吴清平,丁郁,等. 含有特异性分子靶标的空肠弯曲菌标准菌株及其检测和应用,PCT/CN2021/087079 7、王涓,吴清平,丁郁,等. 含有特异性分子靶标的小肠结肠炎耶尔森氏菌标准菌株及其检测和应用,PCT/CN2021/087078 |